The fact that the fastest car in the world, the Bugatti Veyron, has also been deemed to have the worst fuel economy by the EPA would surprise no-one with even the flimsiest grasp of physics. To be fair, there was a bit more to the report than just the fact that a car with an 8-liter quad-turbo W16 engine isn't a rival for the Prius. The top ten best slots weren't entirely dominated by hybrids, but they were all small and mostly (big shock) Japanese.
Considering Bugatti has only built a couple hundred Veyrons, they probably won't be a huge threat to the environment. This is the case with pretty much all of the cars at the bottom. They will be bought almost exclusively by those with access to the huge amounts of money generated by the sale of gasoline.